Liverpool’s revival was short-lived after a 1-0 defeat at Bournemouth on Saturday as Tottenham took advantage of the race for a top-four finish by beating Nottingham Forest 3-1.
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Jurgen Klopp’s men thrashed Manchester United 7-0 last weekend to beat the Red Devils’ record.
But Liverpool suffered another setback in a frustrating season as Mohamed Salah conceded a penalty in the second half.
Philip Billing scored the only goal in the 28th minute as Bournemouth’s first home win since November lifted the Cherries out of the bottom three.
“The game was quite a contrast to what we want to show and do today. I think we played for 95 minutes, the game that Bournemouth wanted,” said Klopp.
“This game is a big knock and how it’s a knock, you have to take it, you have to see how big the scar is and then go from there.”
Fifth-placed Liverpool are now six points off the Champions League places after Harry Kane ensured a difficult week for Spurs ended on a high.
The England captain’s future has been a source of speculation after Tottenham crashed out of the FA Cup and Champions League in the space of a week.
Antonio Conte’s men had failed to score in their previous three games, but Kane ended that drought by heading in a Pedro Porro cross.
Kane then calmly slotted home his first penalty since missing a vital spot-kick in England’s World Cup quarter-final against France.
Conte named Richarlison in the starting line-up despite criticism from the Brazilian coach after he left Europe for AC Milan in midweek.
Richarlison made amends by handing Son Heung-min to fire in Spurs’ number three.
Joe Worrall pulled a goal back for Forest, who then also had a stoppage time penalty from Andre Ayew saved by Fraser Forster.
– Lineker sees Leicester lose –
Gary Lineker made the most of his absence from the BBC’s flagship football highlights program Match of the Day to watch his beloved Leicester lose 3-1 to Chelsea.
Lineker was forced to “resign” from his role after comparing the UK government’s rhetoric towards refugees this week to Nazi-era Germany.
Leicester remain rooted in the relegation battle, just one point above the drop zone after losing five times in a row.
Ben Chilwell put Chelsea ahead early against his former club before Patson Daka levelled.
But a sensational pass from Enzo Fernandez and a finish from Kai Havertz put Chelsea back in front and Mateo Kovacic’s strike secured a third successive win for the Blues, who continue to pile the pressure on Graham Potter.
Everton moved out of the bottom three and into 15th thanks to their third 1-0 win in four home games under Sean Dyche.
Dwight McNeil scored the only goal in the first minute to end Brentford’s 12 game unbeaten run in the Premier League.
Leeds remained second from bottom but closed to a point of safety after twice coming from behind to draw 2-2 at home to high-flying Brighton.
Alexis Mac Allister put the Seagulls in front before Patrick Bamford leveled before the break.
Jack Harrison then scored at both ends in the second half to leave Brighton still nine points off the top four, albeit with three games in hand.
Manchester City can close within two points of leaders Arsenal later when they travel to Crystal Palace.
Arsenal are out of action until Sunday when they face Fulham.